4D Molecular Therapeutics Appoints Noriyuki Kasahara, MD,


EMERYVILLE, Calif., Sept. 27, 2022 (GLOBE NEWSWIRE) — 4D Molecular Therapeutics, Inc. (Nasdaq: FDMT), a clinical-stage biotherapeutics firm harnessing the facility of directed evolution for focused genetic medicines, introduced the appointment of Noriyuki (‘Nori’) Kasahara, MD, PhD to the Board of Directors. In addition, 4DMT introduced the promotion of Fred Kamal, PhD to President and Chief Operating Officer, marking an growth of the breadth and accountability of Dr. Kamal’s position as a member of the senior management staff.

“Together with our Executive Chairman, John Milligan, I am thrilled to welcome Nori to our Board as we continue to advance each of our five product candidates in clinical development and enhance our genetic medicine platform,” mentioned David Kirn, MD, Co-founder and Chief Executive Officer of 4DMT. “Nori’s translational and genetic medicine expertise, which includes the application of genetic medicine technologies across a broad range of therapeutic areas, will support the current and future development of the 4DMT therapeutic vector evolution platform and the development of genetic medicines for sustainable large-market diseases. I am also pleased to announce the promotion of Fred Kamal, PhD, to the role of President and Chief Operating Officer,” added Kirn. “Fred’s vast experience and dedication to 4DMT’s mission will propel our continued success and growth as he takes on this expanded role.”

“I am tremendously excited to join 4DMT, with its immense potential to generate novel targeted genetic medicines through its powerful platform technology,” mentioned Nori Kasahara, MD, PhD. “I look forward to complementing the existing translational medicine expertise of 4DMT’s Board and executive management team as the company generates value, not only through clinical translation and validation of 4DMT’s five current product candidates, but also through continued advancement of its platform.”

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Dr. Kasahara is Professor and Alvera L. Kan Endowed Chair of Neurological Surgery and Radiation Oncology on the University of California San Francisco (“UCSF”), and a principal investigator within the UCSF Brain Tumor Center. He has greater than 30 years of expertise within the fields of gene remedy and genetic engineering, is the creator of greater than 150 peer-reviewed articles and an inventor on 18 issued patents in these fields. The objectives of Dr. Kasahara’s analysis embrace optimizing the applying of a number of and various viral vector supply techniques to attain maximal therapeutic potential, in addition to creating next-generation gene switch applied sciences with better therapeutic efficacy in vivo. Dr. Kasahara serves as a member of the Global Outreach Committee for the American Society of Gene and Cell Therapy, is a previous president of the International Society for Cell and Gene Therapy of Cancer, and is on the Board of Directors of the Japan Society of Gene and Cell Therapy.

About 4DMT

4DMT is a clinical-stage biotherapeutics firm harnessing the facility of directed evolution for focused genetic medicines. 4DMT seeks to unlock the complete potential of genetic medicines utilizing its platform, Therapeutic Vector Evolution, which mixes the facility of directed evolution with roughly one billion artificial capsid sequences to invent focused and advanced vectors to be used in our merchandise. The firm is initially centered on 5 clinical-stage merchandise in three therapeutic areas for each uncommon and enormous market illnesses: ophthalmology, cardiology (together with Fabry illness) and pulmonology. The 4DMT focused and advanced vectors are invented with the purpose of being delivered at comparatively low doses by means of clinically routine, well-tolerated and minimally invasive routes of administration, transducing diseased cells in goal tissues effectively, having lowered immunogenicity and, the place related, having resistance to pre-existing antibodies. The 5 4DMT product candidates in medical growth are: 4D-150 for moist AMD, 4D-310 for Fabry illness, 4D-710 for cystic fibrosis, 4D-125 for XLRP, and 4D-110 for choroideremia.

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4D-150, 4D-310, 4D-710, 4D-125, and 4D-110 are in medical trials and haven’t but been authorised for advertising and marketing by the US FDA or some other regulatory authority. No illustration is made as to the protection or effectiveness of 4D-150, 4D-310, 4D-710, 4D-125, and 4D-110 for the therapeutic use for which they’re being studied. 4D Molecular Therapeutics™, 4DMT™, Therapeutic Vector Evolution™, and the 4DMT brand are emblems of 4DMT.

Forward-Looking Statements

This press launch accommodates forward-looking statements inside the that means of the Private Securities Litigation Reform Act of 1995, as amended, together with, with out limitation, implied and specific statements concerning plans for the medical growth of 4D-310, 4D-125, 4D-110, 4D-150 and 4D-710, together with the therapeutic potential and medical advantages thereof. The phrases “may,” “might,” “will,” “could,” “would,” “should,” “expect,” “plan,” “anticipate,” “intend,” “believe,” “expect,” “estimate,” “seek,” “predict,” “future,” “project,” “potential,” “continue,” “target” and comparable phrases or expressions are meant to establish forward-looking statements, though not all forward-looking statements comprise these figuring out phrases. Any forward-looking statements on this press launch are based mostly on administration’s present expectations and beliefs and are topic to various dangers, uncertainties and vital elements that will trigger precise occasions or outcomes to vary materially from these expressed or implied by any forward-looking statements contained on this press launch, together with dangers and uncertainties which are described in better element within the part entitled “Risk Factors” in 4D Molecular Therapeutics’ most up-to-date Quarterly Report on Form 10-Q, in addition to any subsequent filings with the Securities and Exchange Commission. In addition, any forward-looking statements symbolize 4D Molecular Therapeutics’ views solely as of as we speak and shouldn’t be relied upon as representing its views as of any subsequent date. 4D Molecular Therapeutics explicitly disclaims any obligation to replace any forward-looking statements. No representations or warranties (expressed or implied) are made in regards to the accuracy of any such forward-looking statements.

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Katherine Smith
Evoke Canale


Mike Zanoni
VP, Investor Relations & Corporate Affairs

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