TOKYO, Japan:
Kirin Holdings Company, Limited (Kirin Holdings) and Kao Corporation (Kao) will take part within the “Wakayama Health Promotion Study” cohort research*1 led by Wakayama Medical University and compiled by the Health Promotion Research Center (HPRC), a non-profit group, from this month. Kirin Holdings and Kao will collectively conduct analysis to research the connection between visceral fats and the exercise of plasma cytoid dendritic cells*2 (pDCs), a key chief of the immune system, amongst others.
*1 One of the observational analysis strategies used to look at the affiliation between illness elements and illness onset. A gaggle of individuals concerned in a particular illness issue and a bunch of individuals not concerned in a particular illness issue are created, and the affiliation between elements and illness onset may be examined by calculating the incidence of the goal illness in every group.
*2 Immune cells that play an vital function as a key chief when micro organism or viruses enter the physique. pDC activation prompts varied immune cells reminiscent of NK cells, T cells, and B cells to guard in opposition to viral infections.
Research Outline
- Research theme
Research on genetic and environmental elements associated to the event of lifestyle-related illnesses amongst native residents in Wakayama Prefecture - Research Structure
Kirin Central Research Institute, Kirin Holdings Company, Limited
R&D-Health & Wellness Products Research, R&D-Biological Science Research , Kao Corporation
Wakayama Medical University - Targets
300 male and feminine adults residing in Wakayama Prefecture (deliberate)
Background
Obesity is outlined by the World Health Organization (WHO) as “abnormal or excessive fat accumulation that may impair health,” resulting in an elevated threat of continual illnesses. The results of weight problems on well being are being studied around the globe; and lately, the hyperlink between weight problems and immunity has been attracting consideration, as weight problems has been linked to extra extreme viral infections*3.
Objective
This analysis goals to elucidate the connection between visceral fats and pDC exercise by combining Kirin Holdings’ greater than 35 years of analysis capabilities within the area of immunology with Kao’s analysis capabilities in bettering visceral fats accumulation, which is on the root of lifestyle-related illnesses. The analysis can be performed as an extra research to the “Wakayama Health Promotion Study,” which has been performed on residents of Wakayama Prefecture since 2011.
This month, a particular well being checkup can be performed in Wakayama Prefecture for residents aged 40-55. Kao will acquire information on way of life habits and the quantity of visceral fats, whereas Kirin Holdings will acquire information on the exercise of dendritic cells, together with pDCs, within the blood. These information can be mutually shared, and the connection between visceral fats and pDC exercise can be collectively studied and analyzed.
*3 Int J Epidemiol. 2019;48(6):1783-1794. https://doi.org/10.1093/ije/dyz129
Obes Rev. 2020;21(11):e13128. https://doi.org/10.1111/obr.13128
What is the Wakayama Health Promotion Study?
This is a cohort research led by Wakayama Medical University since 2011 and at the moment being performed in collaboration with HPRC, with the purpose of figuring out genetic and environmental elements concerned within the growth of assorted illnesses amongst native residents in Wakayama Prefecture.
So far, analysis has been performed on way of life and muscle mass, and a variety of unique papers on the connection between muscle mass loss and the onset of arteriosclerosis have been printed, in addition to the connection between a historical past of falling down and the quantity of voluntary bodily exercise.
By clarifying the connection between visceral fats mass and pDC exercise via the HPRC research, Kirin and Kao will promote initiatives aimed toward lowering well being dangers for shoppers sooner or later.
About Kirin Holdings
Kirin Holdings Company, Limited is a global firm that operates within the Food & Beverages area (Food & Beverages companies), Pharmaceuticals area (Pharmaceuticals companies), and Health Science area (Health Science business), each in Japan and throughout the globe.
Kirin Holdings can hint its roots to Japan Brewery which was established in 1885. Japan Brewery grew to become Kirin Brewery in 1907. Since then, the corporate expanded its business with fermentation and biotechnology as its core applied sciences, and entered the pharmaceutical business within the Eighties, all of which proceed to be world development facilities. In 2007, Kirin Holdings was established as a pure holding firm and is at the moment specializing in boosting its Health Science area.
Under theKirin Group Vision 2027 (KV 2027), a long-term administration plan launched in 2019, the Kirin Group goals to change into A world chief in CSV*, creating worth throughout our world of Food & Beverages to Pharmaceuticals. Going ahead, the Kirin Group will proceed to leverage its strengths to create each social and financial worth via its companies, with the purpose of attaining sustainable development in company worth.
* Creating Shared Value: mixed added worth for shoppers in addition to for society at giant.
About Kao Corporation
Kao creates high-value-added merchandise and providers that present care and enrichment for the lifetime of all individuals and the planet. Through its portfolio of over 20 main manufacturers reminiscent of Attack, Bioré, Goldwell, Jergens, John Frieda, Kanebo, Laurier, Merries, and Molton Brown, Kao is a part of the on a regular basis lives of individuals in Asia, Oceania, North America, and Europe. Combined with its chemical business, which contributes to a variety of industries, Kao generates about 1,420 billion yen in annual gross sales. Kao employs about 33,500 individuals worldwide and has 135 years of historical past in innovation. Please go to the Kao Group web site for up to date data. https://www.kao.com/global/en/
The Kao Group established its ESG technique, the Kirei Lifestyle Plan, in April 2019. In 2021, Kao launched its Mid-term Plan 2025 (K25), which declares “protecting future lives” and selling “sustainability as the only path” as its imaginative and prescient. The Kao Group will proceed to combine its ESG technique into its administration practices. It may even develop its business, present higher merchandise and providers for shoppers and society, and work towards its objective, “To Realize a Kirei World in Which All Life Lives in Harmony.”
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