Gurugram, Haryana, India:
Cervical most cancers is the fifth commonest most cancers amongst girls globally in keeping with World Health Organization (WHO). India accounts for one-fifth (1/5th ) of the international burden of the illness. Every 12 months in India, roughly 1.23 lakh girls are identified with cervical most cancers and round 67,000 die from the illness. It is the second commonest most cancers affecting girls in India. India has a inhabitants of roughly 43 crores girls aged 15 years and older who’re in danger of creating cervical most cancers.
According to Dr. Mandeep Singh Malhotra (Clinical Lead & Chief Mentor, Art of Healing Cancer [AOHC- www.artofhealingcancer.com]); Surgical Oncologist, “Human Papilloma Virus (HPV) prevalence among cervical cancer patients in India has varied from 87.8% to 96.67%. HPV is key element and a primary reason for the development of cervical cancer. Therefore, preventing HPV infection can prevent majority of cervical cancers. Of more than 100 HPV types, Type 16 and 18 have been categorized as high-risk types, while the rest are low-risk types for cervical cancer. HPV also causes vulvar, vaginal, anal, penile cancers and oropharyngeal (Throat) cancers as well as precancerous lesions of vulva/vagina, genital warts, and respiratory papillomatosis. HPV infections are most of the time asymptomatic, and generally, individuals are not aware of being infected, thus facilitating the spread easily and unknowingly. Most sexually active women get infected with HPV between the ages of 15 and 25 years. HPV is transmitted via sexual contact, through the genital skin and mucosa rather than in body fluids.”
Dr. Sonal Jain ( MD, Art of Healing Cancer); hematopathologist who was concerned in Covaxin and Corbevax improvement elaborated on the varieties of HPV vaccines out there in India, “HPV vaccines are based on virus-like particles (VLPs) that are formed by HPV surface components. VLPs are not infectious because they lack the virus’s DNA. However, they closely resemble the natural virus, and antibodies against the VLPs also have activity against the natural virus. Until now, two HPV vaccines by foreign manufacturers were available in India: the quadrivalent vaccine (Gardasil Merck), and a bivalent vaccine (Cervarix from GlaxoSmithKline).“
GARDASIL, Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant, vaccine provides >90% protection from HPV types which are responsible for 70% to 80% of cervical cancers and at least 90% of cases of genital warts.
CERVARIX [Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant] Recombinant, vaccine which provides protection against cervical cancer but not from genital warts caused by HPV types 6 and 11.
CERVAVAC- Cervavac is the first indigenously developed, quadrivalent human papillomavirus vaccine made by Serum Institute of India (SII), protecting against HPV types 6, 11, 16, and 18. Cervavac was studied in vaccine trials that were started in September 2018 in 12 sites across India. It was launched on September 1, 2022, after the Drugs Controller General of India (DCGI) granted SII market authorization.
Mr. Arpan Talwar (Co-Founder, Art of Healing Cancer) praises, SII and government’s measure of bringing down the cost of CERVAVAC drastically. CERAVAC is almost 10 times cheaper than other brands. This will help the science of cancer prevention in the form of vaccine to reach majority of Indian population and will save large number of women from cervical cancer and men from throat & penile cancer.
Dr. Mandeep reveals that according to National Immunization Program (NIP) HPV vaccine is recommended to all females between 12 to 26 years of age. It can be given from 9 years of age. The response is better in younger age, studies have shown best response up to 14 to 15 years. Research has shown that the two-dose schedule is effective for children under 15. Teens and young adults who begin the vaccine series later, at ages 15 through 26, should receive three doses of the vaccine. US FDA suggests, “If you’re of age 27 to 45, discuss with your doctor whether he or she recommends that you get the HPV vaccine.” The safety supplied by HPV vaccines lasts a very long time. People who obtained HPV vaccines had been adopted for at the very least about 12 years, and their safety towards HPV remained excessive with no proof of lower over time. The vaccines don’t stop different sexually transmitted ailments, nor do they deal with current HPV infections or HPV-caused illness. Henceforth, the vaccine is handiest earlier than the HPV publicity i.e. earlier than begin of energetic sexual life. It could be given to boys additionally as HPV virus is one of the frequent causes of oropharyngeal and penile most cancers and the vaccine additionally gives safety towards frequent HPV viruses inflicting anogenital warts. In concept, vaccinating boys towards the varieties of HPV related to cervical most cancers may additionally assist defend ladies from the virus by probably lowering transmission. Research has also shown that fewer teens and young adults are getting genital warts and that cervical precancers are decreasing since HPV vaccines have been in use in the United States. More than 12 years of safety monitoring show that the vaccines have caused no serious side effects. The most common problems have been brief soreness and other local symptoms at the injection site. The HPV vaccine isn’t recommended for pregnant women or people who are moderately or severely ill.
Mr. Manjit Singh (Director, Guru Harikrishn Foundation) describes Cervavac to have the potential to reduce cervical cancer incidence by 90% and by making the vaccine indigenous, we can pass on the benefit to majority of India’s inhabitants.
